• Results A total 552 patients (364 men; median age 65 years, interquartile range 54-75) were included. JQ1 cell line In a CT-based model, lower-than-median T5 paravertebral muscle area showed the highest ORs for ICU admission (OR 4.8, 95% CI 2.7-8.5; P less then .001) and death (OR 2.3, 95% CI 1.0-2.9; P=.027). When clinical variables were included…[Read more]

  • Introns impact several vital aspects of eukaryotic organisms like proteomic plasticity, genomic stability, stress response and gene expression. A role for introns in the regulation of gene expression at the level of transcription has been known for more than thirty years. The molecular basis underlying the phenomenon, however, is still not…[Read more]

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