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RESULTS Efficiency of a partial least squares discriminant evaluation (PLS-DA) model for kidney tumefaction in a 22-patient study is 0.96 for location under the receiver running characteristic curve. A PLS-DA model for in vivo breast and lung tumor xenografts executes with 100% sensitivity, 83% specificity, and 89% accuracy. SUMMARY Detection of cancer tumors in surgically resected individual renal cells is demonstrated ex vivo with Vis-NIR MCI, and in vivo on mice with breast or lung xenografts.SIGNIFICANCE 5-Aminolevulinic acid (5-ALA)-based fluorescence assistance in traditional neurosurgical microscopes is bound to strongly fluorescent tumor tissue. Therefore, more sensitive and painful, intrasurgical 5-ALA fluorescence visualization is needed. AIM Macroscopic fluorescence lifetime imaging (FLIM) was done ex vivo on 5-ALA-labeled personal glioma tissue through a surgical microscope to guage its feasibility also to compare it to fluorescence intensity imaging. APPROACH Frequency-domain FLIM ended up being built-into a surgical microscope, which allowed parallel wide-field white-light and fluorescence imaging. We first characterized our system and performed imaging of two types of suspected low-grade glioma, which were when compared with histopathology. RESULTS Our imaging system enabled macroscopic FLIM of a 6.5  ×  6.5  mm2 field of view at spatial resolutions less then 20  μm. A frame of 512  ×  512  pixels with a lifetime accuracy less then 1  ns had been obtained in 65 s. When compared with conventional fluorescence imaging, FLIM considerably highlighted areas with weak 5-ALA fluorescence, that has been in good arrangement with histopathology. CONCLUSIONS Integration of macroscopic FLIM into a surgical microscope is possible and a promising way of improved tumor delineation.The present epidemic circumstance of corona virus disease-19 (COVID-19) still stayed extreme. Given that National Clinical analysis Center for Infectious Diseases, the First Affiliated Hospital of Zhejiang University School of medication is the major medical care center for COVID-19 inZhejiang Province. On the basis of the present expert opinion done by nationwide Health Commission and National Administration of Traditional Chinese Medicine, our team summarized and founded a highly effective treatment mtor signal method devoted to “Four-Anti and Two-Balance” for medical practice. The “Four-Anti and Two-Balance”strategy included antivirus, anti-shock, anti-hyoxemia, anti-secondary infection, and keeping of water, electrolyte and acid base balance and microecological balance. Meanwhile, built-in multidisciplinarypersonalized therapy ended up being advised to enhance healing effect. The necessity of very early viralogical detection, dynamic monitoring of inflammatory indexes and upper body radiograph had been emphasized in clinical deciand lessen the risk of additional illness due to microbial translocation. Anxiety and fear were common in customers with COVID-19. Consequently, we established powerful assessment and caution for psychological crisis. We also integrated Chinese medication in treatment to promote disease rehabilitation through category types of traditional Chinese medicine. We optimized nursing process for serious clients to promote their rehab. It stayed not clear about viral clearance structure after the SARS-CoV-2 disease. Consequently, fourteen days’ quarantine for discharged customers was required and a consistent following up has also been needed.The Zhejiang knowledge above and recommendations happen implemented inside our center and realized good results. But, since COVID-19 had been a newly appearing infection, more work was warranted to boost techniques of prevention, diagnosis and treatment for COVID-19.OBJECTIVE to investigate the dynamic modifications of chest CT images of patients with corona virus disease-19 (COVID-19). METHODS Fifty-two cases of COVID-19 had been admitted in the 1st Affiliated Hospital of Zhejiang University School of drug. The successive chest CT scans were followed up for all patients with an average of 4 scans performed per patient throughout the hospitalization. The shortest interval between each scan had been 2 days and the longest was seven days. The shape, quantity and distribution of lung shadows, as well as the characteristics of this lesions on the CT photos had been reviewed. RESULTS The obvious shadows infiltrating the lungs had been shown on CT pictures in 50 cases, for other 2 cases there was no irregular changes in the lungs through the first CT examination. Ground-glass opacities (GGO) had been found in 48 cases (92.3%), and 19 instances (36.5%) had patchy combination and sub-consolidation, which were accompanied with air bronchi register 17 cases (32.7%). Forty one instances (78.8%) revealed a thickened leaflet interval, 4 instances (7.6%) had a small amount of fibrous stripes. During hospitalization, GGO lesions in COVID-19 patients gradually became rare, the fibrous strip shadows enhanced plus it became the most common imaging manifestation. The lesions quickly progressed in 39 cases (75.0%) within 6-9 days after admission. On days 10-14 of entry, the lesions distinctly solved in 40 situations (76.9%). CONCLUSIONS The chest CT images of patients with COVID-19 have certain qualities with dynamic modifications, which are of value for tracking infection development and clinical treatment.BACKGROUND AND OBJECTIVES Although dietary management is strongly advised in clients with hypertension, bit is known about how precisely many handle their diet and proceed with the directions for high blood pressure. We investigated the prevalence of dietary management among adults with understood hypertension and evaluated their compliance to the nutritional guidelines.